How does the incidence of PTS change over time after DVT?

The incidence of post-thrombotic syndrome (PTS) after deep vein thrombosis (DVT) increases over time. Research has shown that after experiencing a DVT, individuals are at risk of developing PTS, which is characterized by chronic pain, swelling, and other symptoms in the affected limb. The risk of PTS does not remain constant; instead, it is influenced by various factors such as the severity of the initial thrombus, the adequacy of treatment, and the time elapsed since the DVT event.

While some individuals may develop symptoms shortly after the DVT, others may not exhibit significant symptoms until months or even years later. Consequently, studies have documented that the cumulative incidence of PTS often rises over time, reaching a peak several years later. This increasing trend highlights the importance of monitoring individuals who have experienced DVT for the potential onset of PTS as time progresses, reinforcing the need for ongoing assessment and management.