What condition is indicated by a positive Stremmer's sign?

A positive Stremmer's sign is indicative of lymphedema, which is a condition characterized by an accumulation of lymph fluid leading to swelling, commonly in the arms or legs. The Stremmer's sign is tested by attempting to pinch the skin at the base of the second toe (or sometimes the fingers). If the skin cannot be pinched or lifted, it suggests the presence of lymphedema. This is due to the thickening and fibrosis of tissue that occurs as a result of chronic lymphatic obstruction.

In the context of other conditions, deep vein thrombosis primarily involves the blockage of veins and would not result in a Stremmer's sign. Chronic venous insufficiency may cause swelling as well, but it typically presents differently and does not specifically show a positive Stremmer's sign. Arterial disease affects blood flow and may result in different symptoms, such as claudication or skin changes, rather than the signs associated with lymphedema. Therefore, recognizing a positive Stremmer's sign is critical in identifying lymphedema and differentiating it from these other conditions.